with a rubber membrane to simulate movement of the diaphragm. An
air-inlet tube was connected with the trachea, and a tube for injection of
fluid inserted into the pulmonary artery of one lung. The lung with fluid
injected into the pulmonary artery promptly filled with air following
movement of the rubber diaphragm. When this lung was then removed
from the jar, it was found to float in water. The other lung did not inflate,
remained dense, and sank in water.
Under the microscope, the alveoli of the lung injected with fluid were fully
opened, whereas only partial opening had occurred in the other lung.
Jäykkä (1958) reported on the appearance of lungs of pre-term and full-
term infants who died before or shortly after birth, and described two
kinds of expansion: (1) that characteristic of inflation by air only, and
(2) expansion by what he termed "erectile force." .
Inflation with air led to abnormal expansion in an irregular pattern with
large areas of lung remaining uninflated while other areas appeared
overinflated. India ink injections into the pulmonary artery revealed lack
of circulation to areas that failed to inflate. India ink also revealed a
bypass circuit, remnant of prenatal circulation. Infants with irregular lung
expansion of this type also frequently had hyaline membranes and fit
descriptions in the literature of "congenital alveolar dysplasia."
A decade online (2000-2010)
Instrument of harm
>>The first breath
Postnatal placental circulation
Comments for the IACC
Conrad Simon (1963-1995)
Pictures (Conrad & his brothers)
Death in a group home
© Copyright 1999-2010
Eileen Nicole Simon
Conrad Simon Memorial Research Initiative