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    Discussion points 1-3

    1.  Evidence that the auditory system of the brain has higher blood-flow and
    metabolism than any other area of the brain [1, 2].  See figures 1, 2, and 3.

    Note: The deoxyglucose method has been extensively used in animal
    research on brain activity responses to drugs and other factors.  The inferior
    colliculus has consistently been found to have the highest rate of glucose
    utilization in every study.

    2.  Evidence that the auditory system is susceptible to damage by circulatory arrest
    [3-13].  See figures 4, 5, and 6 below.

    Note: Asphyxia at birth was produced in monkeys by preventing the first
    breath and cutting off circulation to the placenta (by clamping the umbilical
    cord).  Ischemic bilaterally symmetric damage to brainstem nuclei resulted.

    Note: Current accepted practice in obstetrics is to clamp the umbilical cord
    immediately after birth, whether or not the first breath has occurred [14].

    3.  Evidence that the auditory system is susceptible to impairment by toxic
    substances.  [15-36].

    Note: Toxic substances cause bilaterally symmetric hemorrhagic (petechial)
    lesions of brainstem nuclei (Wernicke’s encephalopathy).  The lesions are
    petechial, resulting from increased blood flow in response to the insult, with
    bursting of capillaries.  Toxic substances impair aerobic metabolism.
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IACC discussion
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Errors in Neonatology

Discussion points
Supporting evidence

>The auditory system
Final common pathway
Blood-brain barrier
Toxic injury
Brain maturation

Speech comprehension
Birth complications

Figures/ tables
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